The Pentagon detects their arrival and begins tracking them Serena, now governor of Texas, vows to kill them to cover up her attempted murder.

Enraged, Serena uses the shuttle controls to fling them into space, where they are sucked into the black hole. They don their spacesuits and watch Serena through a window as she prepares to change. When Serena volunteers to sacrifice herself, they mistake this for another offer of sex. In space, Beavis and Butt-Head create a catastrophe. They undergo training and board the Space Shuttle Endeavour to study a micro black hole. Impressed, the NASA astronaut Captain Serena Ryan invites them to train as astronauts, which they mistake as an offer for sex. Believing they are at-risk youth, a judge sends them to space camp at the Johnson Space Center, where they become engrossed in a docking simulator. In Highland, Texas, in 1998, Beavis and Butt-Head accidentally burn down their high school science fair.

The film was released on the streaming service Paramount+ on June 23, 2022, to acclaim from critics, who praised the plot, animation, and humor, with many deeming it superior to its predecessor.

The production was conducted remotely via Zoom conferencing due to the COVID-19 pandemic. The film follows teenage delinquents Beavis and Butt-Head, who are transported 24 years from 1998 to 2022, encounter parallel-universe versions of themselves and are hunted by the US government. It is the second film based on the animated television series Beavis and Butt-Head after Beavis and Butt-Head Do America (1996). Beavis and Butt-Head Do the Universe is a 2022 American adult animated science fiction comedy film directed by John Rice and Albert Calleros and written by Mike Judge, Lew Morton, Guy Maxtone-Graham and Ian Maxtone-Graham.

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